Suppression of CFTR premature termination codons and rescue of CFTR protein and function by the synthetic aminoglycoside NB54

Certain aminoglycosides are capable of inducing “translational readthrough” of premature termination codons (PTCs). However, toxicity and relative lack of efficacy deter treatment with clinically available aminoglycosides for genetic diseases caused by PTCs, including cystic fibrosis (CF). Using a s...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Rowe, Steven M., Sloane, Peter, Tang, Li Ping, Backer, Kyle, Mazur, Marina, Buckley-Lanier, Jessica, Nudelman, Igor, Belakhov, Valery, Bebok, Zsuzsa, Schwiebert, Erik, Baasov, Timor, Bedwell, David M.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2011
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204584/
https://ncbi.nlm.nih.gov/pubmed/21779978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-011-0787-6
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים