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Structural insights into anaphase-promoting complex function and mechanism
The anaphase-promoting complex or cyclosome (APC/C) controls sister chromatid segregation and the exit from mitosis by catalysing the ubiquitylation of cyclins and other cell cycle regulatory proteins. This unusually large E3 RING-cullin ubiquitin ligase is assembled from 13 different proteins. Sele...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Royal Society
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3203452/ https://ncbi.nlm.nih.gov/pubmed/22084387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2011.0069 |
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