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Structural insights into anaphase-promoting complex function and mechanism

The anaphase-promoting complex or cyclosome (APC/C) controls sister chromatid segregation and the exit from mitosis by catalysing the ubiquitylation of cyclins and other cell cycle regulatory proteins. This unusually large E3 RING-cullin ubiquitin ligase is assembled from 13 different proteins. Sele...

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Detalles Bibliográficos
Autor Principal: Barford, David
Formato: Artigo
Idioma:Inglês
Publicado: The Royal Society 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203452/
https://ncbi.nlm.nih.gov/pubmed/22084387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2011.0069
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