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STING is a direct innate immune sensor of cyclic-di-GMP
The innate immune system detects infection by employing germline-encoded receptors specific for conserved microbial molecules. Recognition of microbial ligands leads to the production of cytokines, such as type I interferons (IFN), that are essential for successful pathogen elimination. Cytosolic de...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3203314/ https://ncbi.nlm.nih.gov/pubmed/21947006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10429 |
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