Cyclic Di-GMP Stimulates Protective Innate Immunity in Bacterial Pneumonia

Innate immunity is the primary mechanism by which extracellular bacterial pathogens are effectively cleared from the lung. We have previously shown that cyclic di-GMP (c-di-GMP [c-diguanylate]) is a novel small molecule immunomodulator and immunostimulatory agent that triggers protective host innate...

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Detalhes bibliográficos
Main Authors: Karaolis, David K. R., Newstead, Michael W., Zeng, Xianying, Hyodo, Mamoru, Hayakawa, Yoshihiro, Bhan, Urvhashi, Liang, Hallie, Standiford, Theodore J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2044534/
https://ncbi.nlm.nih.gov/pubmed/17646358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01762-06
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