Cyclic Di-GMP Stimulates Protective Innate Immunity in Bacterial Pneumonia

Innate immunity is the primary mechanism by which extracellular bacterial pathogens are effectively cleared from the lung. We have previously shown that cyclic di-GMP (c-di-GMP [c-diguanylate]) is a novel small molecule immunomodulator and immunostimulatory agent that triggers protective host innate...

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Main Authors: Karaolis, David K. R., Newstead, Michael W., Zeng, Xianying, Hyodo, Mamoru, Hayakawa, Yoshihiro, Bhan, Urvhashi, Liang, Hallie, Standiford, Theodore J.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2007
主題:
Host Response and Inflammation
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2044534/
https://ncbi.nlm.nih.gov/pubmed/17646358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01762-06
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