Toll-Like Receptor 9 Regulates the Lung Macrophage Phenotype and Host Immunity in Murine Pneumonia Caused by Legionella pneumophila

Experiments were performed to determine the contribution of TLR9 to the generation of protective immunity against the intracellular respiratory bacterial pathogen Legionella pneumophila. In initial studies, we found that the intratracheal (i.t.) administration of L. pneumophila to mice deficient in...

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Главные авторы: Bhan, Urvashi, Trujillo, Glenda, Lyn-Kew, Kenneth, Newstead, Michael W., Zeng, Xianying, Hogaboam, Cory M., Krieg, Arthur M., Standiford, Theodore J.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2008
Предметы:
Host Response and Inflammation
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2446723/
https://ncbi.nlm.nih.gov/pubmed/18426877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01489-07
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