Toll-Like Receptor 9 Regulates the Lung Macrophage Phenotype and Host Immunity in Murine Pneumonia Caused by Legionella pneumophila

Experiments were performed to determine the contribution of TLR9 to the generation of protective immunity against the intracellular respiratory bacterial pathogen Legionella pneumophila. In initial studies, we found that the intratracheal (i.t.) administration of L. pneumophila to mice deficient in...

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Bibliografski detalji
Glavni autori: Bhan, Urvashi, Trujillo, Glenda, Lyn-Kew, Kenneth, Newstead, Michael W., Zeng, Xianying, Hogaboam, Cory M., Krieg, Arthur M., Standiford, Theodore J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2008
Teme:
Host Response and Inflammation
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2446723/
https://ncbi.nlm.nih.gov/pubmed/18426877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01489-07
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