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Differential Roles of Toll-Like Receptors 2 and 4 in In Vitro Responses of Macrophages to Legionella pneumophila

The role of Toll-like receptors (TLRs) in innate immunity to Legionella pneumophila, a gram-negative facultative intracellular bacterium, was studied by using bone marrow-derived macrophages and dendritic cells from TLR2-deficient (TLR2(−/−)), TLR4(−/−), and wild-type (WT) littermate (C57BL/6 × 129S...

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Main Authors: Akamine, Morikazu, Higa, Futoshi, Arakaki, Noriko, Kawakami, Kazuyoshi, Takeda, Kiyoshi, Akira, Shizuo, Saito, Atsushi
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC538926/
https://ncbi.nlm.nih.gov/pubmed/15618172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.1.352-361.2005
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