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Cyclic di-GMP Sensing via the Innate Immune Signaling Protein STING
Detection of foreign materials is the first step of successful immune responses. Stimulator of interferon genes (STING) was shown to directly bind cyclic diguanylate monophosphate (c-di-GMP), a bacterial second messenger, and to elicit strong interferon responses. Here we elucidate the structural fe...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3697849/ https://ncbi.nlm.nih.gov/pubmed/22705373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.05.029 |
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