Cyclic di-GMP Sensing via the Innate Immune Signaling Protein STING

Detection of foreign materials is the first step of successful immune responses. Stimulator of interferon genes (STING) was shown to directly bind cyclic diguanylate monophosphate (c-di-GMP), a bacterial second messenger, and to elicit strong interferon responses. Here we elucidate the structural fe...

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Main Authors: Yin, Qian, Tian, Yuan, Kabaleeswaran, Venkataraman, Jiang, Xiaomo, Tu, Daqi, Eck, Michael J., Chen, Zhijian J., Wu, Hao
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697849/
https://ncbi.nlm.nih.gov/pubmed/22705373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.05.029
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