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Effect of DNA Groove Binder Distamycin A upon Chromatin Structure

BACKGROUND: Distamycin A is a prototype minor groove binder, which binds to B-form DNA, preferentially at A/T rich sites. Extensive work in the past few decades has characterized the binding at the level of double stranded DNA. However, effect of the same on physiological DNA, i.e. DNA complexed in...

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Détails bibliographiques
Auteurs principaux: Majumder, Parijat, Dasgupta, Dipak
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202541/
https://ncbi.nlm.nih.gov/pubmed/22046291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026486
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