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Effect of DNA Groove Binder Distamycin A upon Chromatin Structure

BACKGROUND: Distamycin A is a prototype minor groove binder, which binds to B-form DNA, preferentially at A/T rich sites. Extensive work in the past few decades has characterized the binding at the level of double stranded DNA. However, effect of the same on physiological DNA, i.e. DNA complexed in...

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Bibliographic Details
Main Authors: Majumder, Parijat, Dasgupta, Dipak
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202541/
https://ncbi.nlm.nih.gov/pubmed/22046291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026486
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