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Effect of DNA Groove Binder Distamycin A upon Chromatin Structure

BACKGROUND: Distamycin A is a prototype minor groove binder, which binds to B-form DNA, preferentially at A/T rich sites. Extensive work in the past few decades has characterized the binding at the level of double stranded DNA. However, effect of the same on physiological DNA, i.e. DNA complexed in...

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Autors principals: Majumder, Parijat, Dasgupta, Dipak
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202541/
https://ncbi.nlm.nih.gov/pubmed/22046291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026486
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