Conditional deletion of epithelial IKKβ impairs alveolar formation through apoptosis and decreased VEGF expression during early mouse lung morphogenesis

BACKGROUND: Alveolar septation marks the beginning of the transition from the saccular to alveolar stage of lung development. Inflammation can disrupt this process and permanently impair alveolar formation resulting in alveolar hypoplasia as seen in bronchopulmonary dysplasia in preterm newborns. NF...

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Hauptverfasser: Londhe, Vedang A, Maisonet, Tiffany M, Lopez, Benjamin, Jeng, Jade-Ming, Xiao, Jing, Li, Changgong, Minoo, Parviz
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2011
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202236/
https://ncbi.nlm.nih.gov/pubmed/21985298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-12-134
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