Conditional deletion of epithelial IKKβ impairs alveolar formation through apoptosis and decreased VEGF expression during early mouse lung morphogenesis

BACKGROUND: Alveolar septation marks the beginning of the transition from the saccular to alveolar stage of lung development. Inflammation can disrupt this process and permanently impair alveolar formation resulting in alveolar hypoplasia as seen in bronchopulmonary dysplasia in preterm newborns. NF...

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Detaylı Bibliyografya
Asıl Yazarlar: Londhe, Vedang A, Maisonet, Tiffany M, Lopez, Benjamin, Jeng, Jade-Ming, Xiao, Jing, Li, Changgong, Minoo, Parviz
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2011
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202236/
https://ncbi.nlm.nih.gov/pubmed/21985298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-12-134
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