Conditional deletion of epithelial IKKβ impairs alveolar formation through apoptosis and decreased VEGF expression during early mouse lung morphogenesis

BACKGROUND: Alveolar septation marks the beginning of the transition from the saccular to alveolar stage of lung development. Inflammation can disrupt this process and permanently impair alveolar formation resulting in alveolar hypoplasia as seen in bronchopulmonary dysplasia in preterm newborns. NF...

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Detalhes bibliográficos
Main Authors: Londhe, Vedang A, Maisonet, Tiffany M, Lopez, Benjamin, Jeng, Jade-Ming, Xiao, Jing, Li, Changgong, Minoo, Parviz
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202236/
https://ncbi.nlm.nih.gov/pubmed/21985298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-12-134
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