Conditional deletion of epithelial IKKβ impairs alveolar formation through apoptosis and decreased VEGF expression during early mouse lung morphogenesis

BACKGROUND: Alveolar septation marks the beginning of the transition from the saccular to alveolar stage of lung development. Inflammation can disrupt this process and permanently impair alveolar formation resulting in alveolar hypoplasia as seen in bronchopulmonary dysplasia in preterm newborns. NF...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Londhe, Vedang A, Maisonet, Tiffany M, Lopez, Benjamin, Jeng, Jade-Ming, Xiao, Jing, Li, Changgong, Minoo, Parviz
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2011
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202236/
https://ncbi.nlm.nih.gov/pubmed/21985298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-12-134
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