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Localized Fgf10 expression is not required for lung branching morphogenesis but prevents differentiation of epithelial progenitors
Localized Fgf10 expression in the distal mesenchyme adjacent to sites of lung bud formation has long been thought to drive stereotypic branching morphogenesis even though isolated lung epithelium branches in the presence of non-directional exogenous Fgf10 in Matrigel. Here, we show that lung agenesi...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Company of Biologists
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3754473/ https://ncbi.nlm.nih.gov/pubmed/23924632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.096560 |
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