Cervicovaginal Safety of the Formulated, Biguanide-Based Human Immunodeficiency Virus Type 1 (HIV-1) Inhibitor NB325 in a Murine Model

Vaginal microbicides that reduce or eliminate the risk of HIV-1 sexual transmission must do so safely without adversely affecting the integrity of the cervicovaginal epithelium. The present studies were performed to assess the safety of the biguanide-based antiviral compound NB325 in a formulation s...

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Detalhes bibliográficos
Main Authors: Lozenski, Karissa, Kish-Catalone, Tina, Pirrone, Vanessa, Rando, Robert F., Labib, Mohamed, Wigdahl, Brian, Krebs, Fred C.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202145/
https://ncbi.nlm.nih.gov/pubmed/22131821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/941061
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