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Persistent Interactions between Biguanide-Based Compound NB325 and CXCR4 Result in Prolonged Inhibition of Human Immunodeficiency Virus Type 1 Infection

We previously demonstrated that the biguanide-based compound NB325 inhibits human immunodeficiency virus type 1 (HIV-1) infection by interacting with the CXCR4 viral coreceptor. This interaction also appeared to be persistent, since HIV-1 infection was inhibited even when the virus was introduced su...

সম্পূর্ণ বিবরণ

সংরক্ষণ করুন:
গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Thakkar, Nina, Pirrone, Vanessa, Passic, Shendra, Keogan, Shawn, Zhu, Wei, Kholodovych, Vladyslav, Welsh, William, Rando, Robert, Labib, Mohamed, Wigdahl, Brian, Krebs, Fred C.
বিন্যাস: Artigo
ভাষা:Inglês
প্রকাশিত: American Society for Microbiology (ASM) 2010
বিষয়গুলি:
অনলাইন ব্যবহার করুন:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863618/
https://ncbi.nlm.nih.gov/pubmed/20231400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00934-09
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