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Decreased cervical epithelial sensitivity to nonoxynol-9 (N-9) after four daily applications in a murine model of topical vaginal microbicide safety

BACKGROUND: The disappointing clinical failures of five topical vaginal microbicides have provided new insights into factors that impact microbicide safety and efficacy. Specifically, the greater risk for human immunodeficiency virus type 1 (HIV-1) acquisition associated with multiple uses of a nono...

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Bibliografski detalji
Glavni autori: Lozenski, Karissa, Ownbey, Robert, Wigdahl, Brian, Kish-Catalone, Tina, Krebs, Fred C
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519674/
https://ncbi.nlm.nih.gov/pubmed/23025553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2050-6511-13-9
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