Mouse Model of Cervicovaginal Toxicity and Inflammation for Preclinical Evaluation of Topical Vaginal Microbicides

Clinical trials evaluating the efficacy of nonoxynol-9 (N-9) as a topical microbicide concluded that N-9 offers no in vivo protection against human immunodeficiency virus type 1 (HIV-1) infection, despite demonstrated in vitro inactivation of HIV-1 by N-9. These trials emphasize the need for better...

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Detalhes bibliográficos
Main Authors: Catalone, Bradley J., Kish-Catalone, Tina M., Budgeon, Lynn R., Neely, Elizabeth B., Ferguson, Maelee, Krebs, Fred C., Howett, Mary K., Labib, Mohamed, Rando, Robert, Wigdahl, Brian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC400576/
https://ncbi.nlm.nih.gov/pubmed/15105142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.5.1837-1847.2004
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