PET Imaging for Attention Deficit Preclinical Drug Testing in Neurofibromatosis-1 Mice

Attention system abnormalities represent a significant barrier to scholastic achievement in children with neurofibromatosis-1 (NF1). Using a novel mouse model of NF1-associated attention deficit (ADD), we demonstrate a presynaptic defect in striatal dopaminergic homeostasis and leverage this finding...

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Bibliographic Details
Main Authors: Brown, Jacquelyn A., Xu, Jinbin, Diggs-Andrews, Kelly A., Wozniak, David F., Mach, Robert H., Gutmann, David H.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202049/
https://ncbi.nlm.nih.gov/pubmed/21963652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2011.09.005
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