Motivational Disturbances and Effects of L-dopa Administration in Neurofibromatosis-1 Model Mice

Children with neurofibromatosis type 1 (NF1) frequently have cognitive and behavioral deficits. Some of these deficits have been successfully modeled in Nf1 genetically-engineered mice that develop optic gliomas (Nf1 OPG mice). In the current study, we show that abnormal motivational influences affe...

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Main Authors: Wozniak, David F., Diggs-Andrews, Kelly A., Conyers, Sara, Yuede, Carla M., Dearborn, Joshua T., Brown, Jacquelyn A., Tokuda, Kazuhiro, Izumi, Yukitoshi, Zorumski, Charles F., Gutmann, David H.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677926/
https://ncbi.nlm.nih.gov/pubmed/23762458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066024
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