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Dopamine deficiency underlies learning deficits in Neurofibromatosis-1 mice

Children with neurofibromatosis type 1 (NF1) are prone to learning and behavioral abnormalities, including problems with spatial learning and attention. The molecular etiology for these deficits is unclear, as previous studies have implicated defective dopamine, cAMP and Ras homeostasis. Using behav...

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Detalhes bibliográficos
Main Authors: Diggs-Andrews, Kelly A., Tokuda, Kazuhiro, Izumi, Yukitoshi, Zorumski, Charles F., Wozniak, David F., Gutmann, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608728/
https://ncbi.nlm.nih.gov/pubmed/23225063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.23793
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