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PET Imaging for Attention Deficit Preclinical Drug Testing in Neurofibromatosis-1 Mice
Attention system abnormalities represent a significant barrier to scholastic achievement in children with neurofibromatosis-1 (NF1). Using a novel mouse model of NF1-associated attention deficit (ADD), we demonstrate a presynaptic defect in striatal dopaminergic homeostasis and leverage this finding...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3202049/ https://ncbi.nlm.nih.gov/pubmed/21963652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2011.09.005 |
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