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Neurofibromatosis-1 Heterozygosity Impairs CNS Neuronal Morphology in a cAMP/PKA/ROCK-Dependent Manner

Children with the neurofibromatosis-1 (NF1) cancer predisposition syndrome exhibit numerous clinical problems that reflect defective central nervous system (CNS) neuronal function, including learning disabilities, attention deficit disorder, and seizures. These clinical features result from reduced...

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Autori principali: Brown, Jacquelyn A., Diggs-Andrews, Kelly A., Gianino, Scott M., Gutmann, David H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237958/
https://ncbi.nlm.nih.gov/pubmed/21903164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2011.08.008
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