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Neurofibromatosis-1 Heterozygosity Impairs CNS Neuronal Morphology in a cAMP/PKA/ROCK-Dependent Manner
Children with the neurofibromatosis-1 (NF1) cancer predisposition syndrome exhibit numerous clinical problems that reflect defective central nervous system (CNS) neuronal function, including learning disabilities, attention deficit disorder, and seizures. These clinical features result from reduced...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3237958/ https://ncbi.nlm.nih.gov/pubmed/21903164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2011.08.008 |
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