Novel Allosteric Sites on Ras for Lead Generation

Aberrant Ras activity is a hallmark of diverse cancers and developmental diseases. Unfortunately, conventional efforts to develop effective small molecule Ras inhibitors have met with limited success. We have developed a novel multi-level computational approach to discover potential inhibitors of pr...

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Detaylı Bibliyografya
Asıl Yazarlar: Grant, Barry J., Lukman, Suryani, Hocker, Harrison J., Sayyah, Jaqueline, Brown, Joan Heller, McCammon, J. Andrew, Gorfe, Alemayehu A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2011
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201956/
https://ncbi.nlm.nih.gov/pubmed/22046245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025711
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