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Systematic and quantitative assessment of the ubiquitin modified proteome

Despite the diverse biological pathways known to be regulated by ubiquitylation, global identification of substrates that are targeted for ubiquitylation has remained a challenge. To globally characterize the ubiquitin-modified proteome (ubiquitinome), we utilized a monoclonal antibody that recogniz...

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Bibliografski detalji
Glavni autori: Kim, Woong, Bennett, Eric J., Huttlin, Edward L., Guo, Ailan, Li, Jing, Possemato, Anthony, Sowa, Mathew E., Rad, Ramin, Rush, John, Comb, Michael J., Harper, J. Wade, Gygi, Steven P.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3200427/
https://ncbi.nlm.nih.gov/pubmed/21906983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.08.025
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