Systematic and quantitative assessment of the ubiquitin modified proteome

Despite the diverse biological pathways known to be regulated by ubiquitylation, global identification of substrates that are targeted for ubiquitylation has remained a challenge. To globally characterize the ubiquitin-modified proteome (ubiquitinome), we utilized a monoclonal antibody that recogniz...

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Autori principali: Kim, Woong, Bennett, Eric J., Huttlin, Edward L., Guo, Ailan, Li, Jing, Possemato, Anthony, Sowa, Mathew E., Rad, Ramin, Rush, John, Comb, Michael J., Harper, J. Wade, Gygi, Steven P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3200427/
https://ncbi.nlm.nih.gov/pubmed/21906983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.08.025
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