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Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics
Dynamic reorganization of signaling systems frequently accompany pathway perturbations, yet quantitative studies of network remodeling by pathway stimuli are lacking. Here, we report the development of a quantitative proteomics platform centered on multiplex Absolute Quantification (AQUA) technology...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3008586/ https://ncbi.nlm.nih.gov/pubmed/21145461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.11.017 |
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