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Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics

Dynamic reorganization of signaling systems frequently accompany pathway perturbations, yet quantitative studies of network remodeling by pathway stimuli are lacking. Here, we report the development of a quantitative proteomics platform centered on multiplex Absolute Quantification (AQUA) technology...

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Main Authors: Bennett, Eric J., Rush, John, Gygi, Steven P., Harper, J. Wade
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3008586/
https://ncbi.nlm.nih.gov/pubmed/21145461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.11.017
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