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Systematic and quantitative assessment of the ubiquitin modified proteome

Despite the diverse biological pathways known to be regulated by ubiquitylation, global identification of substrates that are targeted for ubiquitylation has remained a challenge. To globally characterize the ubiquitin-modified proteome (ubiquitinome), we utilized a monoclonal antibody that recogniz...

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Detalhes bibliográficos
Main Authors: Kim, Woong, Bennett, Eric J., Huttlin, Edward L., Guo, Ailan, Li, Jing, Possemato, Anthony, Sowa, Mathew E., Rad, Ramin, Rush, John, Comb, Michael J., Harper, J. Wade, Gygi, Steven P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3200427/
https://ncbi.nlm.nih.gov/pubmed/21906983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.08.025
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