Pioglitazone Induces a Proadipogenic Antitumor Response in Mice with PAX8-PPARγ Fusion Protein Thyroid Carcinoma

Approximately 35% of follicular thyroid carcinomas harbor a chromosomal translocation that results in expression of a paired box gene 8-peroxisome proliferator-activated receptor γ gene (PPARγ) fusion protein (PPFP). To better understand the oncogenic role of PPFP and its relationship to endogenous...

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Autori principali: Dobson, Melissa E., Diallo-Krou, Ericka, Grachtchouk, Vladimir, Yu, Jingcheng, Colby, Lesley A., Wilkinson, John E., Giordano, Thomas J., Koenig, Ronald J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2011
Soggetti:
Thyroid-TRH-TSH
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199014/
https://ncbi.nlm.nih.gov/pubmed/21952241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-1178
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