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Thyroid-Specific PPARγ Deletion Is Benign in the Mouse

Peroxisome proliferator–activated receptor γ (PPARγ) is widely expressed at low levels and regulates many physiological processes. In mice and humans, there is evidence that PPARγ can function as a tumor suppressor. A PAX8-PPARγ fusion protein (PPFP) is oncogenic in a subset of thyroid cancers, sugg...

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Bibliographic Details
Published in:Endocrinology
Main Authors: Yu, Jingcheng, Koenig, Ronald J.
Format: Artigo
Language:Inglês
Published: Endocrine Society 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839734/
https://ncbi.nlm.nih.gov/pubmed/29420754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2017-03163
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