Brown adipocyte specific PPARγ deletion impairs PVAT development and enhances atherosclerosis in mice

OBJECTIVE: Perivascular adipose tissue (PVAT) contributes to vascular homeostasis by producing paracrine factors. Previously, we reported that selective deletion of peroxisome proliferator-activated receptor gamma (PPARγ) in vascular smooth muscle cells (VSMCs) resulted in concurrent loss of PVAT an...

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Publicat a:Arterioscler Thromb Vasc Biol
Autors principals: Xiong, Wenhao, Zhao, Xiangjie, Villacorta, Luis, Rom, Oren, Garcia-Barrio, Minerva T., Guo, Yanhong, Fan, Yanbo, Zhu, Tianqing, Zhang, Jifeng, Zeng, Rong, Chen, Y Eugene, Jiang, Zhisheng, Chang, Lin
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6202167/
https://ncbi.nlm.nih.gov/pubmed/29954752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.118.311367
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