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The thyroid cancer PAX8-PPARG Fusion Protein activates Wnt/TCF responsive cells that have a transformed phenotype
A chromosomal translocation results in the production of a PAX8-PPARG Fusion Protein (PPFP) in ~35% of follicular thyroid carcinomas. To examine the role of PPFP in thyroid oncogenesis, the fusion protein was stably expressed in the non-transformed rat thyroid cell line PCCL3. PPFP conferred on PCCL...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3839064/ https://ncbi.nlm.nih.gov/pubmed/24025583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-13-0058 |
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