Thiocyanate and hydroxyl ions inactivate the scrapie agent.

To probe the macromolecular structure of the scrapie agent and explore conditions for monomerization, the stability of the agent in low concentrations of inorganic ions was determined. A reduction by a factor of 10(5) in scrapie titer was found on exposure of the agent to 1 M KSCN or 0.3 M NaOH. In...

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出版年:	Proc Natl Acad Sci U S A
主要な著者:	Prusiner, S B, Groth, D F, McKinley, M P, Cochran, S P, Bowman, K A, Kasper, K C
フォーマット:	Artigo
言語:	Inglês
出版事項:	National Academy of Sciences 1981
主題:	Research Article
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319842/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6794034/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.7.4606
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