Thiocyanate and hydroxyl ions inactivate the scrapie agent.
To probe the macromolecular structure of the scrapie agent and explore conditions for monomerization, the stability of the agent in low concentrations of inorganic ions was determined. A reduction by a factor of 10(5) in scrapie titer was found on exposure of the agent to 1 M KSCN or 0.3 M NaOH. In...
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| Yayımlandı: | Proc Natl Acad Sci U S A |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
1981
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319842/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6794034/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.7.4606 |
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