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Targeted nanoparticle enhanced proapoptotic peptide as potential therapy for glioblastoma

Antiangiogenic therapy can produce transient tumor regression in glioblastoma (GBM), but no prolongation in patient survival has been achieved. We have constructed a nanosystem targeted to tumor vasculature that incorporates three elements: (i) a tumor-homing peptide that specifically delivers its p...

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Detalhes bibliográficos
Main Authors: Agemy, Lilach, Friedmann-Morvinski, Dinorah, Kotamraju, Venkata Ramana, Roth, Lise, Sugahara, Kazuki N., Girard, Olivier M., Mattrey, Robert F., Verma, Inder M., Ruoslahti, Erkki
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198371/
https://ncbi.nlm.nih.gov/pubmed/21969599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1114518108
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