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Targeted nanoparticle enhanced proapoptotic peptide as potential therapy for glioblastoma

Antiangiogenic therapy can produce transient tumor regression in glioblastoma (GBM), but no prolongation in patient survival has been achieved. We have constructed a nanosystem targeted to tumor vasculature that incorporates three elements: (i) a tumor-homing peptide that specifically delivers its p...

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Bibliographische Detailangaben
Hauptverfasser: Agemy, Lilach, Friedmann-Morvinski, Dinorah, Kotamraju, Venkata Ramana, Roth, Lise, Sugahara, Kazuki N., Girard, Olivier M., Mattrey, Robert F., Verma, Inder M., Ruoslahti, Erkki
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2011
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198371/
https://ncbi.nlm.nih.gov/pubmed/21969599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1114518108
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