Targeted nanoparticle enhanced proapoptotic peptide as potential therapy for glioblastoma

Antiangiogenic therapy can produce transient tumor regression in glioblastoma (GBM), but no prolongation in patient survival has been achieved. We have constructed a nanosystem targeted to tumor vasculature that incorporates three elements: (i) a tumor-homing peptide that specifically delivers its p...

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Dettagli Bibliografici
Autori principali: Agemy, Lilach, Friedmann-Morvinski, Dinorah, Kotamraju, Venkata Ramana, Roth, Lise, Sugahara, Kazuki N., Girard, Olivier M., Mattrey, Robert F., Verma, Inder M., Ruoslahti, Erkki
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2011
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198371/
https://ncbi.nlm.nih.gov/pubmed/21969599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1114518108
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