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Proapoptotic Peptide-Mediated Cancer Therapy Targeted to Cell Surface p32

Antiangiogenic therapy is a promising new treatment modality for cancer, but it generally produces only transient tumor regression. We have previously devised a tumor-targeted nanosystem, in which a pentapeptide, CGKRK, delivers a proapoptotic peptide into the mitochondria of tumor blood vessel endo...

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Detalhes bibliográficos
Main Authors: Agemy, Lilach, Kotamraju, Venkata R, Friedmann-Morvinski, Dinorah, Sharma, Shweta, Sugahara, Kazuki N, Ruoslahti, Erkki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3863797/
https://ncbi.nlm.nih.gov/pubmed/23959073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.191
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