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Antibiotic acyldepsipeptides activate ClpP peptidase to degrade the cell division protein FtsZ
The worldwide spread of antibiotic-resistant bacteria has lent urgency to the search for antibiotics with new modes of action that are devoid of preexisting cross-resistances. We previously described a unique class of acyldepsipeptides (ADEPs) that exerts prominent antibacterial activity against Gra...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3198362/ https://ncbi.nlm.nih.gov/pubmed/21969594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1110385108 |
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