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Enhancement of antibody class switch recombination by the cumulative activity of four separate elements()
Class switch recombination of antibody isotype is mediated by a recombinational DNA deletion event, and must be robustly upregulated during antigen-driven differentiation of B cells. The enhancer region 3′ of the Cα gene is important for the upregulation of switch recombination. Using a transgene of...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3197901/ https://ncbi.nlm.nih.gov/pubmed/21949022 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101808 |
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