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The role of germline promoters and I exons in cytokine-induced gene-specific class switch recombination

Germline transcription precedes class switch recombination. The promoter regions and I exons of these germline transcripts include binding site for activation- and cytokine-induced transcription factors, and the promoter regions/I exons are essential for class switch recombination. Therefore, it is...

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Bibliographische Detailangaben
Hauptverfasser: Dunnick, Wesley A., Shi, Jian, Holden, Victoria, Fontaine, Clinton, Collins, John T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059604/
https://ncbi.nlm.nih.gov/pubmed/21131417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003108
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