FRNK Inhibits Vascular Smooth Muscle Cell Invasion by Focal Adhesion Targeting, Tyrosine-168 Phosphorylation, and Competition for p130(Cas) Binding

OBJECTIVES: FRNK, the C-terminal domain of focal adhesion kinase (FAK), is a tyrosine-phosphorylated, vascular smooth muscle cell (VSMC)-specific inhibitor of cell migration. FRNK inhibits both FAK and PYK2 in cultured VSMCs, and both kinases may be involved in VSMC invasion during vascular remodeli...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Koshman, Yevgeniya E., Chu, Miensheng, Engman, Steven J., Kim, Taehoon, Iyengar, Rekha, Robia, Seth L., Samarel, Allen M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197899/
https://ncbi.nlm.nih.gov/pubmed/21852560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.235549
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller