Regulation of Connective Tissue Growth Factor Gene Expression and Fibrosis in Human Heart Failure

BACKGROUND: Heart failure (HF) is associated with excessive extracellular matrix (ECM) deposition and abnormal ECM degradation leading to cardiac fibrosis. Connective Tissue Growth Factor (CTGF) modulates ECM production during inflammatory tissue injury, but available data on CTGF gene expression in...

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Main Authors: Koshman, Yevgeniya E., Patel, Nilamkumar, Chu, Miensheng, Iyengar, Rekha, Kim, Taehoon, Ersahin, Cagatay, Lewis, William, Heroux, Alain, Samarel, Allen M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3643143/
https://ncbi.nlm.nih.gov/pubmed/23582094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cardfail.2013.01.013
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