Regulation of Connective Tissue Growth Factor Gene Expression and Fibrosis in Human Heart Failure

BACKGROUND: Heart failure (HF) is associated with excessive extracellular matrix (ECM) deposition and abnormal ECM degradation leading to cardiac fibrosis. Connective Tissue Growth Factor (CTGF) modulates ECM production during inflammatory tissue injury, but available data on CTGF gene expression in...

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Главные авторы: Koshman, Yevgeniya E., Patel, Nilamkumar, Chu, Miensheng, Iyengar, Rekha, Kim, Taehoon, Ersahin, Cagatay, Lewis, William, Heroux, Alain, Samarel, Allen M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3643143/
https://ncbi.nlm.nih.gov/pubmed/23582094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cardfail.2013.01.013
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