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Contractile Activity Regulates Inducible Nitric Oxide Synthase Expression and NO(i) Production in Cardiomyocytes via a FAK-Dependent Signaling Pathway

Intracellular nitric oxide (NO(i)) is a physiological regulator of excitation-contraction coupling, but is also involved in the development of cardiac dysfunction during hypertrophy and heart failure. To determine whether contractile activity regulates nitric oxide synthase (NOS) expression, spontan...

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Autors principals: Chu, Miensheng, Koshman, Yevgeniya, Iyengar, Rekha, Kim, Taehoon, Russell, Brenda, Samarel, Allen M.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412095/
https://ncbi.nlm.nih.gov/pubmed/22900166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/473410
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