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Serine-910 phosphorylation of focal adhesion kinase is critical for sarcomere reorganization in cardiomyocyte hypertrophy

AIMS: Tyrosine-phosphorylated focal adhesion kinase (FAK) is required for the hypertrophic response of cardiomyocytes to growth factors and mechanical load, but the role of FAK serine phosphorylation in this process is unknown. The aims of the present study were to characterize FAK serine phosphoryl...

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Bibliographic Details
Main Authors: Chu, Miensheng, Iyengar, Rekha, Koshman, Yevgeniya E., Kim, Taehoon, Russell, Brenda, Martin, Jody L., Heroux, Alain L., Robia, Seth L., Samarel, Allen M.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246880/
https://ncbi.nlm.nih.gov/pubmed/21937583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvr247
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