A Sucrose-derived Scaffold for Multimerization of Bioactive Peptides

A spherical molecular scaffold bearing eight terminal alkyne groups was synthesized in one step from sucrose. One or more copies of a tetrapeptide azide, either N(3)(CH(2))(5)(C=O)-His-dPhe-Arg-Trp-NH(2) (MSH4) or N(3)(CH(2))(5)(C=O)-Trp-Met-Asp-Phe-NH(2) (CCK4), were attached to the scaffold via th...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Rao, Venkataramanarao, Alleti, Ramesh, Xu, Liping, Tafreshi, Narges K., Morse, David L., Gillies, Robert J., Mash, Eugene A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197697/
https://ncbi.nlm.nih.gov/pubmed/21940174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2011.08.053
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky