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Demonstration of a Sucrose-derived Contrast Agent for Magnetic Resonance Imaging of the GI Tract

A scaffold bearing eight terminal alkyne groups was synthesized from sucrose, and copies of an azide-terminated Gd-DOTA complex were attached via copper(I)-catalyzed azide-alkyne cycloaddition. The resulting contrast agent (CA) was administered by gavage to C3H mice. Passage of the CA through the ga...

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Detalhes bibliográficos
Main Authors: Martinez, Gary V., Navath, Suryakiran, Sewda, Kamini, Rao, Venkataramanarao, Foroutan, Parastou, Alleti, Ramesh, Moberg, Valerie E., Ahad, Ali M., Coppola, Domenico, Lloyd, Mark C., Gillies, Robert J., Morse, David L., Mash, Eugene A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602218/
https://ncbi.nlm.nih.gov/pubmed/23481651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2013.02.008
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