Demonstration of a Sucrose-derived Contrast Agent for Magnetic Resonance Imaging of the GI Tract

A scaffold bearing eight terminal alkyne groups was synthesized from sucrose, and copies of an azide-terminated Gd-DOTA complex were attached via copper(I)-catalyzed azide-alkyne cycloaddition. The resulting contrast agent (CA) was administered by gavage to C3H mice. Passage of the CA through the ga...

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Main Authors: Martinez, Gary V., Navath, Suryakiran, Sewda, Kamini, Rao, Venkataramanarao, Foroutan, Parastou, Alleti, Ramesh, Moberg, Valerie E., Ahad, Ali M., Coppola, Domenico, Lloyd, Mark C., Gillies, Robert J., Morse, David L., Mash, Eugene A.
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602218/
https://ncbi.nlm.nih.gov/pubmed/23481651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2013.02.008
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