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A Solanesol-derived Scaffold for Multimerization of Bioactive Peptides
A flexible molecular scaffold bearing varying numbers of terminal alkyne groups was synthesized in five steps from solanesol. R(CO)-MSH(4)-NH(2) ligands, which have a relatively low affinity for binding at the human melanocortin 4 receptor (hMC4R), were prepared by solid phase synthesis and were N-t...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2929268/ https://ncbi.nlm.nih.gov/pubmed/20701315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo101043m |
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